Triapine
目录号: A14306
Ribonucleotide reductase 抑制剂
Triapine 是一种强效的核糖核苷酸还原酶抑制剂，通过抑制 DNA 合成，具有广谱抗肿瘤活性。
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生物活性
| Discription | Triapine is a potent ribonucleotide reductase inhibitor with broad spectrum antitumor activity by inhibiting DNA synthesis. | |||||
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产品信息
| 目录号 | A14306 |
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| 分子式 | C7H9N5S |
| 分子量 | 195.24 |
| CAS号 | 200933-27-3 |
| SMILES | C1=CC(=C(N=C1)C=NNC(=S)N)N |
| 其他名称 | 3-AP |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 17 mg/mL (87.07 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 5%DMSO+40%PEG300+5%Tween80+50%ddH2O | 1.18 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 51.22 mL | 256.1 mL | 512.19 mL |
| 0.5 mM | 10.24 mL | 51.22 mL | 102.44 mL |
| 1 mM | 5.12 mL | 25.61 mL | 51.22 mL |
| 5 mM | 1.02 mL | 5.12 mL | 10.24 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 200933-27-3 | 200933-27-3 供应商 | 200933-27-3 花费 | 200933-27-3 生产商 | 订购 200933-27-3 | 200933-27-3 代理商