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Tropisetron (ICS 205930)

5-HT3 拮抗剂

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产品目录号: A11226

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Tropisetron 5mg A11226-5
¥ 400.00
Tropisetron 10mg A11226-10
¥ 700.00
Tropisetron 50mg A11226-50
¥ 2,000.00
Tropisetron 100mg A11226-100
¥ 3,200.00
Tropisetron (ICS 205930) 10mM * 1mL in DMSO A11226-10mM-D
¥ 850.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Tropisetron is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic to treat nausea and vomiting following chemotherapy.

Tropisetron (ICS 205930)

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Chemical Information

目录号 A11226
Mechanism of action Antagonist
分子量 320.82
化学分子式 C17H20N2O2.HCl
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 89565-68-4
Synonyms Novaban, ICS 205930
SMILES code CN1[C@@H]2CC[C@H]1CC(C2)OC(=O)C3=CNC4=CC=CC=C43
化学名称 (3-endo)-8-Methyl-8-azabicyclo[3.2. 1]oct-3-yl 1H-indole-3-carboxylic acid ester monohydrochloride

生物活性

Description
Tropisetron is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic to treat nausea and vomiting following chemotherapy.

溶解性

Solubility (25°C)* In vitro DMSO 35 mg/mL (109.09 mM)
Water 64 mg/mL (199.49 mM)
Ethanol Ethanol
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.17 mL 155.85 mL 311.7mL
0.5 mM 6.23 mL 31.17 mL 62.34 mL
1 mM 3.12 mL 15.59 mL 31.17 mL
5 mM 0.62 mL 3.12 mL 6.23 mL

*The above data is based on the productmolecular weight 320.82. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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