Tubacin
目录号: A10954
HDAC6 抑制剂
Tubacin(微管蛋白乙酰化诱导剂)是一种高效、选择性强、可逆的、细胞渗透性 HDAC6 抑制剂,其 IC50 为 4 nM。
Discription | Tubacin (tubulin acetylation inducer) is a highly potent and selective, reversible, cell-permeable HDAC6 inhibitor with an IC50 of 4 nM. | |||||
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Cell Research |
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目录号 | A10954 |
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分子式 | C41H43N3O7S |
分子量 | 721.9 |
CAS号 | 537049-40-4 |
SMILES | C1[C@@H](O[C@@H](O[C@@H]1C2=CC=C(C=C2)CO)C3=CC=C(C=C3)NC(=O)CCCCCCC(=O)NO)CSC4=NC(=C(O4)C5=CC=CC=C5)C6=CC=CC=C6 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 93 mg/mL (128.83 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 2% DMSO+30% PEG 300+5% Tween 80+ddH2O | 9 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 13.85 mL | 69.26 mL | 138.52 mL |
0.5 mM | 2.77 mL | 13.85 mL | 27.7 mL |
1 mM | 1.39 mL | 6.93 mL | 13.85 mL |
5 mM | 0.28 mL | 1.39 mL | 2.77 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2