Tubastatin A HCl

Name: Tubastatin A HCl
SKU: A11042
Price: 280 CNY
Rating: 5 (2 reviews)

目录号: A11042

HDAC6 抑制剂

2 篇发表文献

Tubastatin A 是一种强效且选择性的 HDAC6 抑制剂，在无细胞试验中的 IC50 为 15 nM。它对所有其他同工酶具有1000倍的选择性，除了 HDAC8（57倍）。

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规格	价格	库存
5mg	¥280.00	现货
10mg	¥315.00	现货
25mg	¥420.00	现货
50mg	¥490.00	现货
100mg	¥840.00	现货
200mg	¥1,400.00	现货
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Data Sheet

SDS

Other Forms of Tubastatin A HCl

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Tubastatin A HCl发表的2篇文献

Isin Cakir, .et al. , Nat Metab, 2022, Jan;4(1):44-59 PMID: 35039672

Isin Cakir, .et al. , Elife, 2022, Mar 24 PMID: 35323110

生物活性

Discription

Tubastatin A is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay. It is selective against all the other isozymes (1000-fold) except HDAC8 (57-fold).

Targets

Target	Value

产品信息

目录号	A11042
分子式	C20H21N3O2.HCl
分子量	371.9
CAS号	1310693-92-5, 1239262-52-2
SMILES	CN1CCC2=C(C1)C3=CC=CC=C3N2CC4=CC=C(C=C4)C(=O)NO.Cl
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	67 mg/mL (180.17 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5%DMSO+40%PEG300+5%Tween80+50%ddH2O	5.2 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.89 mL	134.44 mL	268.89 mL
0.5 mM	5.38 mL	26.89 mL	53.78 mL
1 mM	2.69 mL	13.44 mL	26.89 mL
5 mM	0.54 mL	2.69 mL	5.38 mL

Useful Calculator

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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