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Tubastatin A HCl


HDAC6 抑制剂

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产品目录号: A11042


产品名 目录号 价格 数量
Tubastatin A HCl 10mg A11042-10
¥ 600.00
Tubastatin A HCl 25mg A11042-25
¥ 800.00
Tubastatin A HCl 50mg A11042-50
¥ 900.00
Tubastatin A HCl 100mg A11042-100
¥ 1,500.00



Tubastatin A is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay. It is selective against all the other isozymes (1000-fold) except HDAC8 (57-fold).

Tubastatin A HCl




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Chemical Information

目录号 A11042
Mechanism of action Inhibitor
分子量 371.9
化学分子式 C20H21N3O2.HCl
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1310693-92-5, 1239262-52-2
Synonyms N/A
化学名称 N-Hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide hydrochloride


Tubastatin A is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay. It is selective against all the other isozymes (1000-fold) except HDAC8 (57-fold).
Target Value
HDAC6IC50: 15nM
HDAC8IC50: 854nM
HDAC1IC50: 16.4μM
HDAC2IC50: >30μM
HDAC3IC50: >30μM
HDAC4IC50: >30μM
HDAC5IC50: >30μM
HDAC7IC50: >30μM
HDAC9IC50: >30μM
HDAC10IC50: >30μM
HDAC11IC50: >30μM


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.89 mL 134.44 mL 268.89mL
0.5 mM 5.38 mL 26.89 mL 53.78 mL
1 mM 2.69 mL 13.44 mL 26.89 mL
5 mM 0.54 mL 2.69 mL 5.38 mL

*The above data is based on the productmolecular weight 371.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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