TWS119

Name: TWS119
SKU: A11223
Price: 245 CNY
Rating: 5 (288 reviews)

目录号: A11223

GSK-3 抑制剂

TWS119 是一种4,6-二取代吡咯并嘧啶，能强效抑制 GSK3β，其 IC50 值为30纳摩尔。在400纳摩尔时。

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Grouped product items
规格	价格	库存
5mg	¥245.00	现货
10mg	¥455.00	现货
25mg	¥910.00	现货
50mg	¥1,715.00	现货
100mg	¥3,010.00	现货
*10mM 1mL in DMSO**	¥280.00	现货
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Data Sheet

SDS

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生物活性

Discription

TWS119 is a 4,6 disubstituted pyrrolopyrimidine that potently inhibits GSK3β with an IC50 value of 30 nM.1 At 400 nM.

Targets

Target	Value

产品信息

目录号	A11223
分子式	C18H14N4O2
分子量	318.3
CAS号	601514-19-6
SMILES	C1=CC(=CC(=C1)N)C2=CC3=C(N2)N=CN=C3OC4=CC=CC(=C4)O
其他名称	TWS-119
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	58 mg/mL (182.19 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	1% DMSO+30% polyethylene glycol+1% Tween 80	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	31.42 mL	157.08 mL	314.17 mL
0.5 mM	6.28 mL	31.42 mL	62.83 mL
1 mM	3.14 mL	15.71 mL	31.42 mL
5 mM	0.63 mL	3.14 mL	6.28 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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