TWS119

目录号: A11223

GSK-3 Inhibitor

TWS119 Chemical Structure

CAS NO. 601514-19-6

TWS119 is a 4,6 disubstituted pyrrolopyrimidine that potently inhibits GSK3β with an IC50 value of 30 nM.1 At 400 nM.

库存: 现货

规格 价格 数量
5 mg
¥ 500.00
10 mg
¥ 750.00
25 mg
¥ 1,600.00
50 mg
¥ 2,500.00
10mM * 1mL in DMSO
¥ 700.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

TWS119 is a 4,6 disubstituted pyrrolopyrimidine that potently inhibits GSK3β with an IC50 value of 30 nM.1 At 400 nM.
Targets
GSK-3β (Cell-free assay)
30 nM
In vitro (25°C) DMSO 64 mg/mL (201.04 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.42 mL 157.08 mL 314.17 mL
0.5 mM 6.28 mL 31.42 mL 62.83 mL
1 mM 3.14 mL 15.71 mL 31.42 mL
5 mM 0.63 mL 3.14 mL 6.28 mL

*The above data is based on the productmolecular weight 318.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11223
MECHANISM OF ACTION Inhibitor
M. Wt 318.3
Formula C18H14N4O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 601514-19-6
Synonyms TWS-119
SMILES C1=CC(=CC(=C1)N)C2=CC3=C(N2)N=CN=C3OC4=CC=CC(=C4)O

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