TX1-85-1
目录号: A16361
Her3 (ErbB3) ligand
TX1-85-1 是一种 ErbB3 抑制剂。TX2-121-1 可能通过一种 变构机制 发挥 Her3-依赖的药理作用,从而干扰 Her3 与其他蛋白质(如 Her3 或 cMet)之间的相互作用,这与此处呈现的结果一致,且不同于常规的激酶抑制剂,后者阻断催化功能。
Discription | TX1-85-1 is ErbB3 inhibitor. TX2-121-1 may exert Her3-dependent pharmacology through an allosteric mechanismthereby disrupting interactions between Her3 and other proteins such as Her3 or cMet consistent with results presented here and distinct from conventional kinase inhibitors, which block catalytic function. | ||
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目录号 | A16361 |
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分子式 | C32H36N8O3 |
分子量 | 580.69 |
CAS号 | 1603845-32-4 |
SMILES | C=CC(NC1=CC(C2=NN(C3CCC(N4CCN(C(C)=O)CC4)CC3)C5=NC=NC(N)=C52)=CC=C1OC6=CC=CC=C6)=O |
其他名称 | TX1 85-1, TX185-1, TX1851, TX 1851, TX-1851 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2