UBCS039
目录号: A18961
SIRT6 activator
UBCS039 是首个合成的、特异性的 Sirtuin 6 (SIRT6) 激活剂,在人类肿瘤细胞中诱导自噬,其半数有效浓度(EC50)为38微摩尔。
Discription | UBCS039 is the first synthetic, specific Sirtuin 6 (SIRT6) activator, inducing autophagy in human tumor cells, with an EC50 of 38 μM. | ||
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Targets |
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目录号 | A18961 |
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分子式 | C16H13N3 |
分子量 | 247.29 |
CAS号 | 358721-70-7 |
SMILES | N12C(C(C3=CC=CN=C3)NC4=C2C=CC=C4)=CC=C1 |
其他名称 | UBCS 039, UBCS-039 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 42 mg/mL (169.83 mM) | |
Water | Insoluble | ||
Ethanol | 14 mg/mL (56.61 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 40.44 mL | 202.19 mL | 404.38 mL |
0.5 mM | 8.09 mL | 40.44 mL | 80.88 mL |
1 mM | 4.04 mL | 20.22 mL | 40.44 mL |
5 mM | 0.81 mL | 4.04 mL | 8.09 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2