Ubenimex

目录号: A10958

reversible Protease 抑制剂

Ubenimex

Ubenimex Chemical Structure

CAS NO. 58970-76-6

Ubenimex,也称为NK 421和Bestatin,是CD13抑制剂。Ubenimex通过抑制脂质吞噬相关机制中的Akt信号传导减弱肾细胞癌中获得性索拉非尼耐药性。Ubenimex协同增强抗癌药在肝细胞癌中的作用。Ubenimex通过抑制APN的表达并诱导前列腺癌细胞的自噬细胞死亡来抑制细胞增殖,迁移和侵袭。

库存: 现货

规格 价格 数量
25 mg
¥ 1,500.00
100 mg
¥ 3,300.00
200 mg
¥ 5,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Ubenimex,也称为NK 421和Bestatin,是CD13抑制剂。Ubenimex通过抑制脂质吞噬相关机制中的Akt信号传导减弱肾细胞癌中获得性索拉非尼耐药性。Ubenimex协同增强抗癌药在肝细胞癌中的作用。Ubenimex通过抑制APN的表达并诱导前列腺癌细胞的自噬细胞死亡来抑制细胞增殖,迁移和侵袭。
In vitro DMSO 0.35 mg/mL (1.13 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 32.43 mL 162.14 mL 324.28 mL
0.5 mM 6.49 mL 32.43 mL 64.86 mL
1 mM 3.24 mL 16.21 mL 32.43 mL
5 mM 0.65 mL 3.24 mL 6.49 mL

*The above data is based on the productmolecular weight 308.378. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10958
作用机制 Inhibitor (抑制剂)
M. Wt 308.378
Formula C16H24N2O4
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 58970-76-6
Synonyms Ubenimex, NK 421, NK-421, NK421, Bestatin, NSC 265489, NSC265489, NSC-265489
SMILES CC(C)C[C@@H](C(O)=O)NC([C@@H](O)[C@H](N)CC1=CC=CC=C1)=O

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