UCB-9260
目录号: A22416
TNF signaling 抑制剂
UCB-9260 是一种口服活性化合物,通过稳定三聚体的不对称形式来抑制 TNF 信号。UCB-9260 对 TNF 具有选择性,优于其他超家族成员,并且与 TNF 的结合力相似,Kd 值约为 13 nM。
Discription | UCB-9260, an orally active compound, inhibits TNF signaling by stabilising an asymmetric form of the trimer. UCB-9260 is selective for TNF over other superfamily members, and binds TNF with a similar Kd of 13?nM. |
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目录号 | A22416 |
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分子式 | C26H25N5O |
分子量 | 423.51 |
CAS号 | 1515888-53-5 |
SMILES | OC(C1=CC=NC=C1)C2=NC3=CC=C(C4=CN(C)N=C4)C=C3N2CC5=CC(C)=CC=C5C |
其他名称 | UCB9260,UCB 9260 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2