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Mcl-1 抑制剂

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产品目录号: A14222


产品名 目录号 价格 数量
UMI-77 5mg A14222-5
¥ 1,000.00
UMI-77 10mg A14222-10
¥ 1,600.00
UMI-77 25mg A14222-25
¥ 3,000.00
UMI-77 10mM * 1mL in DMSO A14222-10mM-D
¥ 1,100.00



UMI-77 is a selective Mcl-1 inhibitor with Ki of 490 nM, showing selectivity over other members of Bcl-2 family.





顾客使用 Adooq 产品发表的高质量科研文献

Chemical Information

目录号 A14222
Mechanism of action Inhibitor
分子量 468.34
化学分子式 C18H14BrNO5S2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 518303-20-3
Synonyms UMI 77,UMI77
SMILES code C1=CC=C2C(=C1)C(=CC(=C2O)SCC(=O)O)NS(=O)(=O)C3=CC=C(C=C3)Br
化学名称 2-[[4-[[(4-bromophenyl)sulfonyl]amino]-1-hydroxy-2-naphthalenyl]thio]-acetic acid


UMI-77 is a selective Mcl-1 inhibitor with Ki of 490 nM, showing selectivity over other members of Bcl-2 family.
490 nM(Ki)


Solubility (25°C)* In vitro DMSO 93 mg/mL (198.57 mM)
Water <1 mg/mL (<1 mM)
Ethanol 93 mg/mL heating (198.57 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.35 mL 106.76 mL 213.52mL
0.5 mM 4.27 mL 21.35 mL 42.7 mL
1 mM 2.14 mL 10.68 mL 21.35 mL
5 mM 0.43 mL 2.14 mL 4.27 mL

*The above data is based on the productmolecular weight 468.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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