UMI-77
目录号: A14222
Mcl-1 抑制剂
UMI-77 是一种选择性的 Mcl-1 抑制剂，Ki 值为 490 nM，相较于 Bcl-2 家族的其他成员显示出较高的选择性。
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生物活性
| Discription | UMI-77 is a selective Mcl-1 inhibitor with Ki of 490 nM, showing selectivity over other members of Bcl-2 family. | |||||
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产品信息
| 目录号 | A14222 |
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| 分子式 | C18H14BrNO5S2 |
| 分子量 | 468.34 |
| CAS号 | 518303-20-3 |
| SMILES | C1=CC=C2C(=C1)C(=CC(=C2O)SCC(=O)O)NS(=O)(=O)C3=CC=C(C=C3)Br |
| 其他名称 | UMI 77,UMI77 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 92 mg/mL (196.43 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 92 mg/mL (196.43 mM) | ||
| In vivo | 5% DMSO+30% PEG 300+dd H2O | 5 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.35 mL | 106.76 mL | 213.52 mL |
| 0.5 mM | 4.27 mL | 21.35 mL | 42.7 mL |
| 1 mM | 2.14 mL | 10.68 mL | 21.35 mL |
| 5 mM | 0.43 mL | 2.14 mL | 4.27 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 518303-20-3 | 518303-20-3 供应商 | 518303-20-3 花费 | 518303-20-3 生产商 | 订购 518303-20-3 | 518303-20-3 代理商