UMI-77

目录号: A14222

Mcl-1 抑制剂

UMI-77

UMI-77 Chemical Structure

CAS NO. 518303-20-3

UMI-77是一种选择性的Mcl-1抑制剂,Ki为490 nM,显示出对Bcl-2家族其他成员的选择性。

库存: 现货

规格 价格 数量
5 mg
¥ 1,000.00
10 mg
¥ 1,600.00
25 mg
¥ 3,000.00
10mM * 1mL in DMSO
¥ 1,100.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

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UMI-77是一种选择性的Mcl-1抑制剂,Ki为490 nM,显示出对Bcl-2家族其他成员的选择性。
靶点信息
Mcl-1
490 nM(Ki)
In vitro (25°C) DMSO 92 mg/mL (196.43 mM)
Water Insoluble
Ethanol Warmed: 92 mg/mL (196.43 mM)
In vivo 5% DMSO+30% PEG 300+dd H2O 5 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.35 mL 106.76 mL 213.52 mL
0.5 mM 4.27 mL 21.35 mL 42.7 mL
1 mM 2.14 mL 10.68 mL 21.35 mL
5 mM 0.43 mL 2.14 mL 4.27 mL

*The above data is based on the productmolecular weight 468.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A14222
作用机制 Inhibitor (抑制剂)
M. Wt 468.34
Formula C18H14BrNO5S2
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 518303-20-3
Synonyms UMI 77,UMI77
SMILES C1=CC=C2C(=C1)C(=CC(=C2O)SCC(=O)O)NS(=O)(=O)C3=CC=C(C=C3)Br

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