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Umibecestat (CNP520)

目录号: A18987
BACE-1 抑制剂
Umibecestat (CNP520) 是一种β-位点淀粉样前体蛋白裂解酶-1(BACE-1)抑制剂,其对人类 BACE-1 和小鼠 BACE-1 的半抑制浓度(IC50)分别为11 nM和10 nM。
Grouped product items
规格 价格 库存 数量
1mg
¥1,190.00
现货
5mg
¥2,415.00
现货
10mg
¥3,710.00
现货
25mg
¥6,230.00
现货
50mg
¥8,505.00
现货
100mg
¥11,515.00
现货
10mM * 1mL in DMSO
¥3,150.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription Umibecestat (CNP520) is a beta-site amyloid precursor protein cleaving enzyme-1 (BACE-1) inhibitor with IC50s of 11 nM and 10 nM for human BACE-1 and mouse BACE-1, respectively.
Cell Research
Cell Line Type Value Description References
产品信息
目录号 A18987
分子式 C19H15ClF7N5O2
分子量 513.8
CAS号 1387560-01-1
SMILES O=C(NC1=NC([C@@]2(CO[C@](C)(C(N)=N2)C(F)(F)F)C)=C(C=C1)F)C3=NC=C(C=C3Cl)C(F)(F)F
其他名称 CNP 520, CNP-520
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

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    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

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    C2

    V2

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