UNC 9994 hydrochloride

目录号: A16087

dopamine D2 receptor 激动剂

UNC 9994 hydrochloride

UNC 9994 hydrochloride Chemical Structure

CAS NO. 1354030-51-5

UNC 9994 hydrochloride,独特的,β-arrestin偏向的功能选择性多巴胺D2受体(D2R)激动剂(Ki值为30 nM;在ε-arrestin-2募集试验中EC50值为50 nM),在体内具有抗精神病活性。UNC9994在野生型小鼠中显着抑制了PCP诱导的超运动,而在Δr-arrestin-2基因敲除小鼠中这种作用被完全消除。

库存: 现货

规格 价格 数量
2 mg
¥ 1,500.00
5 mg
¥ 2,800.00
10 mg
¥ 5,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

UNC 9994 hydrochloride,独特的,β-arrestin偏向的功能选择性多巴胺D2受体(D2R)激动剂(Ki值为30 nM;在ε-arrestin-2募集试验中EC50值为50 nM),在体内具有抗精神病活性。UNC9994在野生型小鼠中显着抑制了PCP诱导的超运动,而在Δr-arrestin-2基因敲除小鼠中这种作用被完全消除。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.84 mL 109.21 mL 218.42 mL
0.5 mM 4.37 mL 21.84 mL 43.68 mL
1 mM 2.18 mL 10.92 mL 21.84 mL
5 mM 0.44 mL 2.18 mL 4.37 mL

*The above data is based on the productmolecular weight 457.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A16087
作用机制 Agonist (激动剂)
M. Wt 457.84
Formula C21H23Cl3N2OS
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1354030-51-5
Synonyms UNC9994 hydrochloride
SMILES C1CN(CCC1C2=C(C(=CC=C2)Cl)Cl)CCCOC3=CC4=C(C=C3)SC=N4.Cl

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