UNC0379

Name: UNC0379
SKU: A14320

目录号: A14320

SETD8 HMTase 抑制剂

UNC0379 Chemical Structure

CAS NO. 1620401-82-2

UNC0379是赖氨酸甲基转移酶SETD8的选择性底物竞争性抑制剂。它对SETD8的亲和力已通过ITC（等温滴定热量法）和SPR（表面等离振子共振）研究得到证实。

库存：现货

规格	价格	数量
5 mg	￥ 800.00
10 mg	￥ 1,350.00
25 mg	￥ 2,800.00

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生物活性

UNC0379是赖氨酸甲基转移酶SETD8的选择性底物竞争性抑制剂。它对SETD8的亲和力已通过ITC（等温滴定热量法）和SPR（表面等离振子共振）研究得到证实。

靶点信息

SETD8
7.9 μM

溶解度 *

In vitro	DMSO	79 mg/mL (191.02 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.2 mL	120.98 mL	241.97 mL
0.5 mM	4.84 mL	24.2 mL	48.39 mL
1 mM	2.42 mL	12.1 mL	24.2 mL
5 mM	0.48 mL	2.42 mL	4.84 mL

*The above data is based on the productmolecular weight 413.28. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A14320
作用机制	Inhibitor (抑制剂)
M. Wt	413.28
Formula	C23H35N5O2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1620401-82-2
Synonyms	UNC-0379, UNC 0379
SMILES	COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCCC3)NCCCCCN4CCCC4)OC