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UNC0638

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G9a/GLP HMTase 抑制剂

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产品目录号: A12947

库存状态:中国现货中国现货

产品名 目录号 价格 数量
UNC0638 10mg A12947-10
¥ 800.00
UNC0638 25mg A12947-25
¥ 1,500.00
UNC0638 50mg A12947-50
¥ 2,400.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

UNC0638 is an inhibitor of protein lysine methyltransferases G9a(IC50<15 nM) and GLP(IC50=19 nM) with excellent potency and selectivity over a wide range of epigenetic and non-epigenetic targets.

UNC0638

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Chemical Information

目录号 A12947
Mechanism of action Inhibitor
分子量 509.72
化学分子式 C30H47N5O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1255580-76-7
Synonyms UNC 0638, UNC-0638
SMILES code CC(C)N1CCC(CC1)NC2=NC(=NC3=CC(=C(C=C32)OC)OCCCN4CCCC4)C5CCCCC5
化学名称 2-cyclohexyl-6-methoxy-N-(1-propan-2-ylpiperidin-4-yl)-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine

生物活性

Description
UNC0638 is an inhibitor of protein lysine methyltransferases G9a(IC50<15 nM) and GLP(IC50=19 nM) with excellent potency and selectivity over a wide range of epigenetic and non-epigenetic targets.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.62 mL 98.09 mL 196.19mL
0.5 mM 3.92 mL 19.62 mL 39.24 mL
1 mM 1.96 mL 9.81 mL 19.62 mL
5 mM 0.39 mL 1.96 mL 3.92 mL

*The above data is based on the productmolecular weight 509.72. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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