UNC0638
目录号: A12947
G9a/GLP HMTase 抑制剂
UNC0638 是一种针对蛋白质赖氨酸甲基转移酶 G9a(IC50<15 nM)和 GLP(IC50=19 nM)的抑制剂,具有出色的效力和选择性,超过了广泛的表观遗传和非表观遗传靶标。
Discription | UNC0638 is an inhibitor of protein lysine methyltransferases G9a(IC50<15 nM) and GLP(IC50=19 nM) with excellent potency and selectivity over a wide range of epigenetic and non-epigenetic targets. | |||||
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Cell Research |
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目录号 | A12947 |
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分子式 | C30H47N5O2 |
分子量 | 509.72 |
CAS号 | 1255580-76-7 |
SMILES | CC(C)N1CCC(CC1)NC2=NC(=NC3=CC(=C(C=C32)OC)OCCCN4CCCC4)C5CCCCC5 |
其他名称 | UNC 0638, UNC-0638 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 87 mg/mL (170.68 mM) | |
Water | 5 mg/mL (9.81 mM) | ||
Ethanol | 87 mg/mL (170.68 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 19.62 mL | 98.09 mL | 196.19 mL |
0.5 mM | 3.92 mL | 19.62 mL | 39.24 mL |
1 mM | 1.96 mL | 9.81 mL | 19.62 mL |
5 mM | 0.39 mL | 1.96 mL | 3.92 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2