UNC0642

目录号: A15487

G9a/GLP inhibitor

UNC0642 Chemical Structure

CAS NO. 1481677-78-4

UNC0642 is a potent and selective G9a and GLP histone lysine methyltransferase inhibitor (IC50 < 2.5 nM). It reduces H3K9 dimethylation levels in MDA-MB-231 cells (IC50 = 110 nM). Displays modest brain penetration in vivo.

库存: 现货

规格 价格 数量
10 mg
¥ 1,500.00
25 mg
¥ 3,000.00
50 mg
¥ 4,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

UNC0642 is a potent and selective G9a and GLP histone lysine methyltransferase inhibitor (IC50 < 2.5 nM). It reduces H3K9 dimethylation levels in MDA-MB-231 cells (IC50 = 110 nM). Displays modest brain penetration in vivo.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.29 mL 91.46 mL 182.92 mL
0.5 mM 3.66 mL 18.29 mL 36.58 mL
1 mM 1.83 mL 9.15 mL 18.29 mL
5 mM 0.37 mL 1.83 mL 3.66 mL

*The above data is based on the productmolecular weight 546.69. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A15487
MECHANISM OF ACTION Inhibitor
M. Wt 546.69
Formula C29H44F2N6O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1481677-78-4
Synonyms UNC 0642, UNC-0642
SMILES CC(C)N1CCC(CC1)NC2=NC(=NC3=CC(=C(C=C32)OC)OCCCN4CCCC4)N5CCC(CC5)(F)F

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