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UNC0646

促销

G9a/GLP HMTase 抑制剂

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产品目录号: A13194

库存状态:中国现货中国现货

产品名 目录号 价格 数量
UNC0646 10mg A13194-10
¥ 1,000.00
UNC0646 25mg A13194-25
¥ 2,000.00
UNC0646 50mg A13194-50
¥ 3,500.00
UNC0646 100mg A13194-100
¥ 6,000.00
UNC0646 10mM * 1mL in DMSO A13194-10mM-D
¥ 800.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

UNC0646 is a potent and selective inhibitor of the homologous protein lysine methyltransferases, G9a and GLP (IC50 values are 6 nM and 15 nM for G9a and GLP, respectively).

UNC0646

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Chemical Information

目录号 A13194
Mechanism of action Inhibitor
分子量 621.9
化学分子式 C36H59N7O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1320288-17-2
Synonyms UNC 0646, UNC-0646
SMILES code CC(C)N1CCCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)NC4CCN(CC4)C5CCCCC5)OC)OCCCN6CCCCC6
化学名称 N-(1-Cyclohexyl-4-piperidinyl)-2-[h?exahydro-4-(1-methylethyl)-1H-1,4-diazepin-1-yl]-6?-methoxy-7-[3-(1-piperidinyl)propoxy]-4-quinazolin?amine

生物活性

Description
UNC0646 is a potent and selective inhibitor of the homologous protein lysine methyltransferases, G9a and GLP (IC50 values are 6 nM and 15 nM for G9a and GLP, respectively).

溶解性

Solubility (25°C)* In vitro DMSO 100 mg/mL (149.29 mM)
Water 100 mg/mL (149.29 mM)
Ethanol 100 mg/mL (149.29 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.08 mL 80.4 mL 160.8mL
0.5 mM 3.22 mL 16.08 mL 32.16 mL
1 mM 1.61 mL 8.04 mL 16.08 mL
5 mM 0.32 mL 1.61 mL 3.22 mL

*The above data is based on the productmolecular weight 621.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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