产品详情
UNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor, binds in the MerTK ATP pocket, with an IC50 of 4.4 nM, more selective over Axl, Tyro3 and Flt3. UNC2541 inhibits phosphorylated MerTK (pMerTK; EC50, 510 nM).
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 21.21 mL | 106.03 mL | 212.06 mL |
0.5 mM | 4.24 mL | 21.21 mL | 42.41 mL |
1 mM | 2.12 mL | 10.6 mL | 21.21 mL |
5 mM | 0.42 mL | 2.12 mL | 4.24 mL |
*The above data is based on the productmolecular weight 471.57. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A18523 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 471.57 |
Formula | C24H34FN7O2 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 1612782-86-1 |
Synonyms | UNC 2541, UNC-2541 |
SMILES | O=C(C(C(NCCCC[C@@H]1N)=N2)=CN=C2NCCCCCCNC1=O)NCC3=CC=C(F)C=C3 |
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