UNC2541

目录号: A18523

Mer tyrosine kinase inhibitor

UNC2541

UNC2541 Chemical Structure

CAS NO. 1612782-86-1

UNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor, binds in the MerTK ATP pocket, with an IC50 of 4.4 nM, more selective over Axl, Tyro3 and Flt3. UNC2541 inhibits phosphorylated MerTK (pMerTK; EC50, 510 nM).

库存: 现货

规格 价格 数量
5 mg
¥ 3,000.00
10 mg
¥ 5,500.00
50 mg
¥ 18,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

UNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor, binds in the MerTK ATP pocket, with an IC50 of 4.4 nM, more selective over Axl, Tyro3 and Flt3. UNC2541 inhibits phosphorylated MerTK (pMerTK; EC50, 510 nM).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.21 mL 106.03 mL 212.06 mL
0.5 mM 4.24 mL 21.21 mL 42.41 mL
1 mM 2.12 mL 10.6 mL 21.21 mL
5 mM 0.42 mL 2.12 mL 4.24 mL

*The above data is based on the productmolecular weight 471.57. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A18523
作用机制 Inhibitor (抑制剂)
M. Wt 471.57
Formula C24H34FN7O2
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1612782-86-1
Synonyms UNC 2541, UNC-2541
SMILES O=C(C(C(NCCCC[C@@H]1N)=N2)=CN=C2NCCCCCCNC1=O)NCC3=CC=C(F)C=C3

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