Urelumab is a fully human IgG4 monoclonal antibody that functions as a CD137 agonist without binding to its natural ligand. This antibody is designed to potentiate the antitumor activities of T-cells and natural killer (NK) cells. Additionally, Urelumab has been shown to potentially enhance the cytotoxic effects of Rituximab. It is primarily utilized in research focused on various non-Hodgkin lymphomas, including diffuse large B-cell lymphoma and follicular lymphoma. This makes Urelumab a valuable tool in the study of immune-mediated cancer therapies.
Urelumab is a fully human IgG4 monoclonal antibody that functions as a CD137 agonist without binding to its natural ligand. This antibody is designed to potentiate the antitumor activities of T-cells and natural killer (NK) cells. Additionally, Urelumab has been shown to potentially enhance the cytotoxic effects of Rituximab. It is primarily utilized in research focused on various non-Hodgkin lymphomas, including diffuse large B-cell lymphoma and follicular lymphoma. This makes Urelumab a valuable tool in the study of immune-mediated cancer therapies.
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