Ustekinumab is a human monoclonal antibody of the IgG1?? subclass that targets interleukin-12 (IL-12) and interleukin-23 (IL-23). This biologic is engineered to bind specifically to the p40 protein subunit shared by these cytokines, thereby inhibiting their interaction with the IL-12R??1 receptor and modulating immune responses involved in inflammatory pathways. Ustekinumab is utilized primarily in the study of immune-mediated disorders and has applications in the research of diseases such as psoriasis, Crohn?€?s disease, and other chronic inflammatory conditions.
Ustekinumab is a human monoclonal antibody of the IgG1?? subclass that targets interleukin-12 (IL-12) and interleukin-23 (IL-23). This biologic is engineered to bind specifically to the p40 protein subunit shared by these cytokines, thereby inhibiting their interaction with the IL-12R??1 receptor and modulating immune responses involved in inflammatory pathways. Ustekinumab is utilized primarily in the study of immune-mediated disorders and has applications in the research of diseases such as psoriasis, Crohn?€?s disease, and other chronic inflammatory conditions.
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