Vadadustat
目录号: A16794
HIF prolyl-hydroxylase 抑制剂
Vadadustat，也被称为 AKB-6548 和 PG-1016548，是一种强效的低氧诱导因子-脯氨酸双加氧酶抑制剂。
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生物活性
| Discription | Vadadustat, also known as AKB-6548 and PG-1016548, is a potent Hypoxia-inducible factor-proline dioxygenase inhibitor. |
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产品信息
| 目录号 | A16794 |
|---|---|
| 分子式 | C14H11ClN2O4 |
| 分子量 | 306.7 |
| CAS号 | 1000025-07-9 |
| SMILES | C1=CC(=CC(=C1)Cl)C2=CC(=C(N=C2)C(=O)NCC(=O)O)O |
| 其他名称 | AKB-6548; AKB 6548; AKB6548; PG-1016548; PG 1016548; PG1016548; B-506; B506; |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 59 mg/mL (192.37 mM) | |
| Water | Insoluble | ||
| Ethanol | 9 mg/mL (29.34 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 32.61 mL | 163.03 mL | 326.05 mL |
| 0.5 mM | 6.52 mL | 32.61 mL | 65.21 mL |
| 1 mM | 3.26 mL | 16.3 mL | 32.61 mL |
| 5 mM | 0.65 mL | 3.26 mL | 6.52 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1000025-07-9 | 1000025-07-9 供应商 | 1000025-07-9 花费 | 1000025-07-9 生产商 | 订购 1000025-07-9 | 1000025-07-9 代理商