Vadastuximab is a humanized monoclonal antibody designed to specifically target CD33, a transmembrane receptor expressed on cells predominantly in myeloid lineages. This antibody serves as a foundational component for the development of antibody-drug conjugates (ADCs), notably Vadastuximab talirine. This application highlights its potential in targeted cancer therapy, particularly for the treatment of acute myeloid leukemia (AML) where CD33 is commonly overexpressed.
Vadastuximab is a humanized monoclonal antibody designed to specifically target CD33, a transmembrane receptor expressed on cells predominantly in myeloid lineages. This antibody serves as a foundational component for the development of antibody-drug conjugates (ADCs), notably Vadastuximab talirine. This application highlights its potential in targeted cancer therapy, particularly for the treatment of acute myeloid leukemia (AML) where CD33 is commonly overexpressed.
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