VcMMAE

目录号: A14362

VcMMAE Chemical Structure

CAS NO. 646502-53-6

VcMMAE is an antibody-drug conjugate (ADC) with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE), linked via the lysosomally cleavable dipeptide, valine-citrulline (vc).

库存: 现货

规格 价格 数量
1 mg
¥ 700.00
2 mg
¥ 1,200.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

VcMMAE is an antibody-drug conjugate (ADC) with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE), linked via the lysosomally cleavable dipeptide, valine-citrulline (vc).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 7.6 mL 37.98 mL 75.95 mL
0.5 mM 1.52 mL 7.6 mL 15.19 mL
1 mM 0.76 mL 3.8 mL 7.6 mL
5 mM 0.15 mL 0.76 mL 1.52 mL

*The above data is based on the productmolecular weight 1316.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A14362
MECHANISM OF ACTION
M. Wt 1316.63
Formula C68H105N11O15
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 646502-53-6
Synonyms Vedotin
SMILES CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@@H]([C@@H](C)C(=O)N[C@H](C)[C@H](C2=CC=CC=C2)O)OC)OC)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)N(C)C(=O)OCC3=CC=C(C=C3)NC(=O)[C@H](CCCNC(=O)N)NC(=O)[C@H](C(C)C)NC(=O)CCCCCN4C(=O)C=CC4=O

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