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YAP 抑制剂

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产品目录号: A12658


产品名 目录号 价格 数量
Verteporfin 5mg A12658-5
¥ 800.00
Verteporfin 10mg A12658-10
¥ 1,200.00
Verteporfin 25mg A12658-25
¥ 2,400.00
Verteporfin 50mg A12658-50
¥ 4,000.00
Verteporfin 10mM * 1mL in DMSO A12658-10mM-D
¥ 1,200.00



Verteporfin is a small molecule that inhibits TEAD–YAP association and YAP-induced liver overgrowth. It is also a potent second-generation photosensitizing agent derived from porphyrin.





顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 Verteporfin 发表的文献 (1)
  • Abe T, .et al. Role of YAP Activation in Nuclear Receptor CAR-Mediated Proliferation of Mouse Hepatocytes, Toxicol Sci, 2018, Oct 1;165(2):408-419 PMID: 29893953

Chemical Information

目录号 A12658
Mechanism of action Inhibitor
分子量 718.79
化学分子式 C41H42N4O8
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 129497-78-5
Synonyms Visudyne, DB00460??CL 318,952??Benzoporphyrin D??Bpd-MA??AIDS350621??AIDS-350621??Benzoporphyrin derivative monoacid ring A.
SMILES code CC1=C(C2=CC3=NC(=CC4=C(C(=C(N4)C=C5C6(C(C(=CC=C6C(=N5)C=C1N2)C(=O)OC)C(=O)OC)C)C)CCC(=O)OC)C(=C3C)CCC(=O)O)C=C.CC1=C(C2=CC3=NC(=CC4=C(C(=C(N4)C=C5C6(C(C(=CC=C6C(=N5)C=C1N2)C(=O)OC)C(=O)OC)C)C)CCC(=O)O)C(=C3C)CCC(=O)OC)C=C
化学名称 trans-3,4-Dicarboxy-4,4a-dihydro-4a,8,14,19-tetramethyl-18-vinyl-23H,25H-benzo(b)porphine-9,13-dipropionic acid 3,4,9-trimethyl ester


Verteporfin is a small molecule that inhibits TEAD–YAP association and YAP-induced liver overgrowth. It is also a potent second-generation photosensitizing agent derived from porphyrin.
VDA (Endothelial cells)


Solubility (25°C)* In vitro DMSO 100 mg/mL (139.12 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 13.91 mL 69.56 mL 139.12mL
0.5 mM 2.78 mL 13.91 mL 27.82 mL
1 mM 1.39 mL 6.96 mL 13.91 mL
5 mM 0.28 mL 1.39 mL 2.78 mL

*The above data is based on the productmolecular weight 718.79. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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