产品详情

生物活性

VGX-1027通过抑制Toll样受体4（TLR4）信号传导来显示免疫调节和抗炎活性。

溶解度 *

In vitro (25°C)	DMSO	38 mg/mL (185.17 mM)
	Water	Insoluble
	Ethanol	38 mg/mL (185.17 mM)
In vivo	2% DMSO+30% PEG 300+5% Tween 80+ddH2O	9 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	48.73 mL	243.65 mL	487.31 mL
0.5 mM	9.75 mL	48.73 mL	97.46 mL
1 mM	4.87 mL	24.37 mL	48.73 mL
5 mM	0.97 mL	4.87 mL	9.75 mL

*The above data is based on the productmolecular weight 205.21. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A12548
作用机制	Inhibitor (抑制剂)
M. Wt	205.21
Formula	C11H11NO3
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	6501-72-0
Synonyms	GIT 27, VGX1027, GIT27
SMILES	C1C(ON=C1C2=CC=CC=C2)CC(=O)O