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Vicriviroc Malate

促销

CCR5 拮抗剂

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产品目录号: A10971

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Vicriviroc Malate 5mg A10971-5
¥ 1,200.00
Vicriviroc Malate 10mg A10971-10
¥ 2,000.00
Vicriviroc Malate 50mg A10971-50
¥ 6,000.00
Vicriviroc Malate 100mg A10971-100
¥ 9,800.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Vicriviroc Malate is a second generation orally active CCR5 antagonist, which is also a potent inhibitor of HIV-1 entry into target cells, with a mean IC50 =0.46 nM and IC50 =1~10 nM to HIV isolates (n=52).

Vicriviroc Malate

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顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 Vicriviroc Malate 发表的文献 (1)
  • Tomohiro Nabekura, .et al. Effects of Antiviral Drugs on Organic Anion Transport in Human Placental BeWo Cells, Antimicrob Agents Chemother, 2015, Dec; 59(12): 7666每7670 PMID: 26416870

Chemical Information

目录号 A10971
Mechanism of action Antagonist
分子量 667.7
化学分子式 C28H38F3N5O2.C4H6O5
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 541503-81-5
Synonyms N/A
SMILES code C[C@H]1CN(CCN1[C@@H](COC)C2=CC=C(C=C2)C(F)(F)F)C3(CCN(CC3)C(=O)C4=C(N=CN=C4C)C)C.C(C(C(=O)O)O)C(=O)O
化学名称 1-[(4,6-Dimethyl-5-pyrimidinyl)carbonyl]-4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-piperazinyl]-4-methylpiperidine malate

生物活性

Description
Vicriviroc Malate is a second generation orally active CCR5 antagonist, which is also a potent inhibitor of HIV-1 entry into target cells, with a mean IC50 =0.46 nM and IC50 =1~10 nM to HIV isolates (n=52).

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.98 mL 74.88 mL 149.77mL
0.5 mM 3 mL 14.98 mL 29.95 mL
1 mM 1.5 mL 7.49 mL 14.98 mL
5 mM 0.3 mL 1.5 mL 3 mL

*The above data is based on the productmolecular weight 667.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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