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Vipadenant，也称为BIIB014，CEB-4520，是针对帕金森氏症的有效，选择性和口服腺苷A2A受体拮抗剂。Vipadenant在帕金森氏病的常用模型中显示出强大的口服活性。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.12 mL | 155.6 mL | 311.19 mL |
| 0.5 mM | 6.22 mL | 31.12 mL | 62.24 mL |
| 1 mM | 3.11 mL | 15.56 mL | 31.12 mL |
| 5 mM | 0.62 mL | 3.11 mL | 6.22 mL |
*The above data is based on the productmolecular weight 321.344. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13963 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 321.344 |
| Formula | C16H15N7O? |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 442908-10-3 |
| Synonyms | BIIB014, BIIB-014, BIIB 014, CEB-4520, CEB 4520, CEB4520, V-2006, V2006, V 2006, VER-11135, VER-A00-11, VER-A00049, VER-ADO-49, Vipadenant |
| SMILES | NC1=NC(C2=CC=CO2)=C(N=NN3CC4=CC=C(N)C(C)=C4)C3=N1 |
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