Vixarelimab (KPL-716) is a human monoclonal antibody targeting the beta chain of the oncostatin M (OSM) receptor. By binding to this subunit, Vixarelimab effectively inhibits signaling pathways mediated by interleukin-31 (IL-31) and OSM. This antibody is particularly useful in research focused on inflammatory skin conditions, including atopic dermatitis and prurigo nodularis, providing a valuable tool for investigating the molecular mechanisms underlying these diseases and potentially guiding therapeutic interventions.
Vixarelimab (KPL-716) is a human monoclonal antibody targeting the beta chain of the oncostatin M (OSM) receptor. By binding to this subunit, Vixarelimab effectively inhibits signaling pathways mediated by interleukin-31 (IL-31) and OSM. This antibody is particularly useful in research focused on inflammatory skin conditions, including atopic dermatitis and prurigo nodularis, providing a valuable tool for investigating the molecular mechanisms underlying these diseases and potentially guiding therapeutic interventions.
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