Volociximab (M200), a chimeric human/murine IgG4 monoclonal antibody, selectively targets integrin ??5??1 with an EC50 of 0.2 nM. Integrin ??5??1, a principal receptor for fibronectin, plays a crucial role in angiogenesis. Volociximab exhibits potent antiangiogenic and antitumor properties, effectively inhibiting the proliferation of human umbilical vein vascular endothelial cells (HUVECs). This antibody is instrumental in research focused on the mechanisms of angiogenesis and potential therapeutic strategies for cancer treatment.
Volociximab (M200), a chimeric human/murine IgG4 monoclonal antibody, selectively targets integrin ??5??1 with an EC50 of 0.2 nM. Integrin ??5??1, a principal receptor for fibronectin, plays a crucial role in angiogenesis. Volociximab exhibits potent antiangiogenic and antitumor properties, effectively inhibiting the proliferation of human umbilical vein vascular endothelial cells (HUVECs). This antibody is instrumental in research focused on the mechanisms of angiogenesis and potential therapeutic strategies for cancer treatment.
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