Voriconazole (Vfend)
目录号: A10978
CYP17 抑制剂
Voriconazole(Vfend)是一种三唑类抗真菌药物,以冻干粉末形式提供,用于制备静脉注射溶液。
Discription | Voriconazole (Vfend) is a triazole antifungal agent that is available as a lyophilized powder for solution for intravenous infusion. | ||
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目录号 | A10978 |
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分子式 | C16H14F3N5O |
分子量 | 349.3 |
CAS号 | 137234-62-9 |
SMILES | C[C@@H](C1=NC=NC=C1F)[C@](CN2C=NC=N2)(C3=C(C=C(C=C3)F)F)O |
其他名称 | Vfend,Pfizer |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 65 mg/mL (186.08 mM) | |
Water | Insoluble | ||
Ethanol | 19 mg/mL (54.39 mM) | ||
In vivo | 2% DMSO+30% PEG 300+2% Tween 80+ddH2O | 7 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 28.63 mL | 143.14 mL | 286.29 mL |
0.5 mM | 5.73 mL | 28.63 mL | 57.26 mL |
1 mM | 2.86 mL | 14.31 mL | 28.63 mL |
5 mM | 0.57 mL | 2.86 mL | 5.73 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2