Vortioxetine

Name: Vortioxetine
SKU: A21266

目录号: A21266

5-HT1A/5-HT1B/5-HT3A/5-HT7 receptor/SERT inhibitor

Vortioxetine Chemical Structure

CAS NO. 508233-74-7

Vortioxetine is a inhibitor of 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT, with Ki values of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively.

库存：现货

规格	价格	数量
5 mg	￥ 760.00
10 mg	￥ 1,300.00
50 mg	￥ 3,860.00
100 mg	￥ 7,730.00

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生物活性

Vortioxetine is a inhibitor of 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT, with Ki values of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively.

溶解度 *

In vitro	DMSO	29 mg/mL (97.17 mM)
	Water	Insoluble
	Ethanol	24 mg/mL (80.41 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	33.51 mL	167.53 mL	335.06 mL
0.5 mM	6.7 mL	33.51 mL	67.01 mL
1 mM	3.35 mL	16.75 mL	33.51 mL
5 mM	0.67 mL	3.35 mL	6.7 mL

*The above data is based on the productmolecular weight 298.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A21266
作用机制	Inhibitor (抑制剂)
M. Wt	298.45
Formula	C18H22N2S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	508233-74-7
Synonyms	Lu AA 21004
SMILES	CC1=CC=C(SC2=CC=CC=C2N3CCNCC3)C(C)=C1