Voxelotor (GBT-440)
目录号: A20863
HbS polymerization 抑制剂
Voxelotor(GBT 440)是一种口服生物利用度的镰状血红蛋白(HbS)聚合抑制剂。
Discription | Voxelotor (GBT 440) is an orally bioavailable sickle hemoglobin (HbS) polymerization inhibitor. |
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目录号 | A20863 |
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分子式 | C19H19N3O3 |
分子量 | 337.37 |
CAS号 | 1446321-46-5 |
SMILES | OC1=CC=CC(OCC2=C(C3=CC=NN3C(C)C)N=CC=C2)=C1C=O |
其他名称 | GBT 440, GBT-440, GBT440 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 60 mg/mL (177.84 mM) | |
Water | Insoluble | ||
Ethanol | 60 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 29.64 mL | 148.21 mL | 296.41 mL |
0.5 mM | 5.93 mL | 29.64 mL | 59.28 mL |
1 mM | 2.96 mL | 14.82 mL | 29.64 mL |
5 mM | 0.59 mL | 2.96 mL | 5.93 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2