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Voxelotor

Voxelotor

Name: Voxelotor
SKU: A20863

目录号: A20863

HbS polymerization inhibitor

Voxelotor Chemical Structure

CAS NO. 1446321-46-5

Voxelotor (GBT 440) is an orally bioavailable sickle hemoglobin (HbS) polymerization inhibitor.

库存：现货

规格	价格	数量
5 mg	￥ 900.00
10 mg	￥ 1,550.00
50 mg	￥ 4,600.00
100 mg	￥ 9,200.00

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生物活性

Voxelotor (GBT 440) is an orally bioavailable sickle hemoglobin (HbS) polymerization inhibitor.

溶解度 *

In vitro	DMSO	60 mg/mL (177.84 mM)
	Water	Insoluble
	Ethanol	60 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	29.64 mL	148.21 mL	296.41 mL
0.5 mM	5.93 mL	29.64 mL	59.28 mL
1 mM	2.96 mL	14.82 mL	29.64 mL
5 mM	0.59 mL	2.96 mL	5.93 mL

*The above data is based on the productmolecular weight 337.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A20863
作用机制	Inhibitor (抑制剂)
M. Wt	337.37
Formula	C19H19N3O3
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1446321-46-5
Synonyms	GBT 440, GBT-440, GBT440
SMILES	OC1=CC=CC(OCC2=C(C3=CC=NN3C(C)C)N=CC=C2)=C1C=O