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VPS34-IN1

Vps34 抑制剂

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产品目录号: A15874

库存状态:中国现货中国现货

产品名 目录号 价格 数量
VPS34-IN1 5mg A15874-5
¥ 900.00
VPS34-IN1 10mg A15874-10
¥ 1,600.00
VPS34-IN1 25mg A15874-25
¥ 3,500.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Vps34-IN1 is a potent and highly selective Vps34 inhibitor with IC50 of 25 nM invitro,which does not significantly inhibit the isoforms of class I as well as class II PI3Ks.

VPS34-IN1

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Chemical Information

目录号 A15874
Mechanism of action Inhibitor
分子量 425.91
化学分子式 C21H24ClN7O
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1383716-33-3
Synonyms PS34 IN1, VPS34IN1
SMILES code OC(C)(C)CNC(N=C1CC2CC2)=NC=C1C3=CC=NC(NC4=CC=NC(Cl)=C4)=N3
化学名称 2-Propanol, 1-[[2-[(2-chloro-4-pyridinyl)amino]-4'-(cyclopropylmethyl)[4,5'-bipyrimidin]-2'-yl]amino]-2-methyl-

生物活性

Description
Vps34-IN1 is a potent and highly selective Vps34 inhibitor with IC50 of 25 nM invitro,which does not significantly inhibit the isoforms of class I as well as class II PI3Ks.
Targets
Vps34
25 nM

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.48 mL 117.4 mL 234.79mL
0.5 mM 4.7 mL 23.48 mL 46.96 mL
1 mM 2.35 mL 11.74 mL 23.48 mL
5 mM 0.47 mL 2.35 mL 4.7 mL

*The above data is based on the productmolecular weight 425.91. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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