VPS34-IN1
目录号: A15874
Vps34 抑制剂
Vps34-IN1 是一种效力强大且高度选择性的 Vps34 抑制剂,体外 IC50 为 25 nM,它并不显著抑制 class I 和 class II PI3Ks 的同种型。
Discription | Vps34-IN1 is a potent and highly selective Vps34 inhibitor with IC50 of 25 nM invitro,which does not significantly inhibit the isoforms of class I as well as class II PI3Ks. | ||
---|---|---|---|
Targets |
|
目录号 | A15874 |
---|---|
分子式 | C21H24ClN7O |
分子量 | 425.91 |
CAS号 | 1383716-33-3 |
SMILES | OC(C)(C)CNC(N=C1CC2CC2)=NC=C1C3=CC=NC(NC4=CC=NC(Cl)=C4)=N3 |
其他名称 | PS34 IN1, VPS34IN1 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 73 mg/mL (171.4 mM) | |
Water | Insoluble | ||
Ethanol | 73 mg/mL (171.4 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 23.48 mL | 117.4 mL | 234.79 mL |
0.5 mM | 4.7 mL | 23.48 mL | 46.96 mL |
1 mM | 2.35 mL | 11.74 mL | 23.48 mL |
5 mM | 0.47 mL | 2.35 mL | 4.7 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2