VR23

目录号: A13650

Proteasome inhibitor‎

VR23 Chemical Structure

CAS NO. 1624602-30-7

VR23 is a small molecule that potently inhibited the activities of trypsin-like proteasomes (IC50 = 1 nM), chymotrypsin-like proteasomes (IC50 = 50-100 nM), and caspase-like proteasomes (IC50 = 3uM).

库存: 现货

规格 价格 数量
5 mg
¥ 650.00
10 mg
¥ 1,100.00
25 mg
¥ 2,200.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

VR23 is a small molecule that potently inhibited the activities of trypsin-like proteasomes (IC50 = 1 nM), chymotrypsin-like proteasomes (IC50 = 50-100 nM), and caspase-like proteasomes (IC50 = 3uM).
Targets
Trypsin-like proteasomes Chymotrypsin-like proteasomes Caspase-like proteasomes
1 nM50-100 nM3 μM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.93 mL 104.63 mL 209.26 mL
0.5 mM 4.19 mL 20.93 mL 41.85 mL
1 mM 2.09 mL 10.46 mL 20.93 mL
5 mM 0.42 mL 2.09 mL 4.19 mL

*The above data is based on the productmolecular weight 477.88. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A13650
MECHANISM OF ACTION Inhibitor
M. Wt 477.88
Formula C19H16ClN5O6S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1624602-30-7
Synonyms VR-23, VR 23
SMILES ClC1=CC2=C(C(N3CCN(S(C4=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C4)(=O)=O)CC3)=CC=N2)C=C1

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