VRC-01 is a fully human monoclonal antibody of the IgG1 subclass that specifically targets the gp120 envelope glycoprotein of HIV-1. This antibody inhibits viral entry into host cells by emulating the binding mechanism of the CD4 receptor with the HIV-1 gp120 envelope glycoprotein, thereby blocking the virus's ability to infect cells. For experimental control purposes, Human IgG1 kappa, Isotype Control, is recommended. VRC-01 serves as a critical tool in the study of HIV pathogenesis and the development of therapeutic strategies against HIV infection.
VRC-01 is a fully human monoclonal antibody of the IgG1 subclass that specifically targets the gp120 envelope glycoprotein of HIV-1. This antibody inhibits viral entry into host cells by emulating the binding mechanism of the CD4 receptor with the HIV-1 gp120 envelope glycoprotein, thereby blocking the virus's ability to infect cells. For experimental control purposes, Human IgG1 kappa, Isotype Control, is recommended. VRC-01 serves as a critical tool in the study of HIV pathogenesis and the development of therapeutic strategies against HIV infection.
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