VS-5584

Name: VS-5584
SKU: A12480

目录号: A12480

PI3K/mTOR 抑制剂

VS-5584 Chemical Structure

CAS NO. 1246560-33-7

VS-5584是一种新型且高度选择性的PI3K/mTOR激酶抑制剂，可用于治疗癌症。

库存：现货

规格	价格	数量
10 mg	￥ 1,200.00
25 mg	￥ 2,500.00
50 mg	￥ 4,000.00
10mM * 1mL in DMSO	￥ 950.00

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生物活性

VS-5584是一种新型且高度选择性的PI3K/mTOR激酶抑制剂，可用于治疗癌症。

靶点信息

PI3Kα	PI3Kδ	PI3Kγ	mTOR	PI3Kβ
2.6 nM	2.7 nM	3.0 nM	3.4 nM	21 nM

溶解度 *

In vitro (25°C)	DMSO	70 mg/mL (197.51 mM)
	Water	Insoluble
	Ethanol	3 mg/mL (8.46 mM)
In vivo	0.5% methylcellulose+0.2% Tween 80	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	28.22 mL	141.08 mL	282.16 mL
0.5 mM	5.64 mL	28.22 mL	56.43 mL
1 mM	2.82 mL	14.11 mL	28.22 mL
5 mM	0.56 mL	2.82 mL	5.64 mL

*The above data is based on the productmolecular weight 354.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A12480
作用机制	Inhibitor (抑制剂)
M. Wt	354.41
Formula	C17H22N8O
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1246560-33-7
Synonyms	SB2343, VS5584, SB-2343, SB 2343
SMILES	CC1=NC2=C(N=C(N=C2N1C(C)C)N3CCOCC3)C4=CN=C(N=C4)N