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VTX-2337是一种具有潜在的免疫刺激和抗肿瘤活性的小分子Toll样受体8（TLR8）激动剂。
靶点信息
| TLR8 | ||||
| 100 nM(EC50) |
| In vitro | DMSO | Warmed: 48 mg/mL (104.67 mM) | |
| Water | Insoluble | ||
| Ethanol | 13 mg/mL (28.34 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.81 mL | 109.03 mL | 218.05 mL |
| 0.5 mM | 4.36 mL | 21.81 mL | 43.61 mL |
| 1 mM | 2.18 mL | 10.9 mL | 21.81 mL |
| 5 mM | 0.44 mL | 2.18 mL | 4.36 mL |
*The above data is based on the productmolecular weight 458.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A12841 |
|---|---|
| 作用机制 | Agonist (激动剂) |
| M. Wt | 458.6 |
| Formula | C28H34N4O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 926927-61-9 |
| Synonyms | VTX2337, VTX 2337 |
| SMILES | CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C3=CC=C(C=C3)C(=O)N4CCCC4)N=C(C1)N |
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