VU 0357121

目录号: A11754

mGluR5 PAM

VU 0357121

VU 0357121 Chemical Structure

CAS NO. 433967-28-3

VU 0357121 is a positive allosteric modulator (PAM) of the metabotropic glutamate receptor 5 (mGlu5) with EC50 = 33 nM, 92% Glumax.

库存: 现货

规格 价格 数量
10 mg
¥ 900.00
25 mg
¥ 2,000.00
50 mg
¥ 3,800.00
100 mg
¥ 7,000.00
10mM * 1mL in DMSO
¥ 860.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

VU 0357121 is a positive allosteric modulator (PAM) of the metabotropic glutamate receptor 5 (mGlu5) with EC50 = 33 nM, 92% Glumax.
Targets
mGluR5
30 nM(EC50)
In vitro DMSO 61 mg/mL (199.79 mM)
Water <1 mg/mL (<1 mM)
Ethanol 21 mg/mL (68.78 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 32.75 mL 163.77 mL 327.55 mL
0.5 mM 6.55 mL 32.75 mL 65.51 mL
1 mM 3.28 mL 16.38 mL 32.75 mL
5 mM 0.66 mL 3.28 mL 6.55 mL

*The above data is based on the productmolecular weight 305.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11754
MECHANISM OF ACTION N/A
M. Wt 305.3
Formula C17H17F2NO2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 433967-28-3
Synonyms VU0357121,VU-0357121
SMILES CCCCOC1=CC=C(C=C1)C(=O)NC2=C(C=C(C=C2)F)F

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