VU 0357121

目录号: A11754

mGluR5 PAM

VU 0357121

VU 0357121 Chemical Structure

CAS NO. 433967-28-3

VU 0357121是代谢型谷氨酸受体5(mGlu5)的正变构调节剂(PAM),EC50 = 33 nM,Glumax为92%。

库存: 现货

规格 价格 数量
10 mg
¥ 900.00
25 mg
¥ 2,000.00
50 mg
¥ 3,800.00
100 mg
¥ 7,000.00
10mM * 1mL in DMSO
¥ 860.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

VU 0357121是代谢型谷氨酸受体5(mGlu5)的正变构调节剂(PAM),EC50 = 33 nM,Glumax为92%。
靶点信息
mGluR5
30 nM(EC50)
In vitro DMSO 56 mg/mL (183.41 mM)
Water Insoluble
Ethanol 19 mg/mL (62.23 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 32.75 mL 163.77 mL 327.55 mL
0.5 mM 6.55 mL 32.75 mL 65.51 mL
1 mM 3.28 mL 16.38 mL 32.75 mL
5 mM 0.66 mL 3.28 mL 6.55 mL

*The above data is based on the productmolecular weight 305.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11754
M. Wt 305.3
Formula C17H17F2NO2
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 433967-28-3
Synonyms VU0357121,VU-0357121
SMILES CCCCOC1=CC=C(C=C1)C(=O)NC2=C(C=C(C=C2)F)F

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