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VU 0361737

mGlu4 receptors modulator

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产品目录号: A12467


产品名 目录号 价格 数量
VU 0361737 10mg A12467-10
¥ 700.00
VU 0361737 25mg A12467-25
¥ 1,500.00
VU 0361737 50mg A12467-50
¥ 2,400.00
VU 0361737 10mM * 1mL in DMSO A12467-10mM-D
¥ 550.00



VU 0361737 is a selective positive allosteric modulator at mGluR-4 (EC50 values are 240 and 110 nM at human and rat receptors respectively).

VU 0361737




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Chemical Information

目录号 A12467
Mechanism of action Modulator
分子量 262.69
化学分子式 C13H11ClN2O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1161205-04-4
Synonyms VU-0361737, VU0361737
SMILES code COC1=C(C=CC(=C1)NC(=O)C2=CC=CC=N2)Cl
化学名称 N-(4-Chloro-3-methoxyphenyl)-2-pyridinecarboxamide


VU 0361737 is a selective positive allosteric modulator at mGluR-4 (EC50 values are 240 and 110 nM at human and rat receptors respectively).
mGluR4 (Rat ) mGluR4 (Human)
110 nM(EC50)240 nM(EC50)


Solubility (25°C)* In vitro DMSO 53 mg/mL (201.75 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 38.07 mL 190.34 mL 380.68mL
0.5 mM 7.61 mL 38.07 mL 76.14 mL
1 mM 3.81 mL 19.03 mL 38.07 mL
5 mM 0.76 mL 3.81 mL 7.61 mL

*The above data is based on the productmolecular weight 262.69. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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