VU 0364439

目录号: A12664

GluR modulator

VU 0364439 Chemical Structure

CAS NO. 1246086-78-1

VU 0364439 is a positive allosteric modulator (PAM) of mGlu4 receptors (EC50 = 19.8 nM in vitro for human mGlu4).

库存: 现货

规格 价格 数量
10 mg
¥ 600.00
25 mg
¥ 1,200.00
50 mg
¥ 2,000.00
100 mg
¥ 6,500.00
10mM * 1mL in DMSO
¥ 840.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

VU 0364439 is a positive allosteric modulator (PAM) of mGlu4 receptors (EC50 = 19.8 nM in vitro for human mGlu4).
Targets
mGluR4
19.8 nM(EC50)
In vitro DMSO 85 mg/mL (201.28 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.68 mL 118.4 mL 236.8 mL
0.5 mM 4.74 mL 23.68 mL 47.36 mL
1 mM 2.37 mL 11.84 mL 23.68 mL
5 mM 0.47 mL 2.37 mL 4.74 mL

*The above data is based on the productmolecular weight 422.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12664
MECHANISM OF ACTION Modulator
M. Wt 422.29
Formula C18H13Cl2N3O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1246086-78-1
Synonyms VU0364439,VU-0364439
SMILES C1=CC=C(C(=C1)NS(=O)(=O)C2=C(C=C(C=C2)NC(=O)C3=CC=CC=N3)Cl)Cl

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