VU 0364770
目录号: A12139
mGlu4 receptors modulator
VU 0364770 是 mGlu4 受体的正向异构调节剂,在表达 mGlu4 的 HEK 293 细胞中的 EC50 值为 290 nM。
| Discription | VU 0364770 is a positive allosteric modulator at mGlu4 receptors with EC50 value of 290 nM in mGlu4-expressing HEK 293 cells. | ||
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| 目录号 | A12139 |
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| 分子式 | C12H9ClN2O |
| 分子量 | 232.67 |
| CAS号 | 61350-00-3 |
| SMILES | C1=CC=NC(=C1)C(=O)NC2=CC(=CC=C2)Cl |
| 其他名称 | VU0364770 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 46 mg/mL (197.7 mM) | |
| Water | Insoluble | ||
| Ethanol | 46 mg/mL (197.7 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 42.98 mL | 214.9 mL | 429.79 mL |
| 0.5 mM | 8.6 mL | 42.98 mL | 85.96 mL |
| 1 mM | 4.3 mL | 21.49 mL | 42.98 mL |
| 5 mM | 0.86 mL | 4.3 mL | 8.6 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2