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VU0453379 is a CNS-penetrant glucagon-like peptide 1 receptor (GLP-1R) positive allosteric modulator (PAM) with an EC50 of 1.3 μM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.01 mL | 115.05 mL | 230.11 mL |
| 0.5 mM | 4.6 mL | 23.01 mL | 46.02 mL |
| 1 mM | 2.3 mL | 11.51 mL | 23.01 mL |
| 5 mM | 0.46 mL | 2.3 mL | 4.6 mL |
*The above data is based on the productmolecular weight 434.58. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A18796 |
|---|---|
| 作用机制 | Modulator (调节剂) |
| M. Wt | 434.58 |
| Formula | C26H34N4O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1638646-27-1 |
| Synonyms | VU0453379; VU-0453379; VU 0453379; |
| SMILES | O=C(C(C1=C2N(C)C3=C1C=CC=C3)=CN(C4CCCC4)C2=O)NC[C@H]5N(C(C)C)CCC5 |
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