VX-661

Name: VX-661
SKU: A12519

目录号: A12519

CFTR corrector

Product Citations (1)

VX-661 Chemical Structure

CAS NO. 1152311-62-0

VX-661是另一种正在开发中的用于治疗囊性纤维化的囊性纤维化跨膜电导调节器（CFTR）校正器。

库存：现货

规格	价格	数量
5 mg	￥ 900.00
10 mg	￥ 1,400.00
25 mg	￥ 2,500.00
50 mg	￥ 4,000.00
10mM * 1mL in DMSO	￥ 1,530.00

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生物活性

VX-661是另一种正在开发中的用于治疗囊性纤维化的囊性纤维化跨膜电导调节器（CFTR）校正器。

靶点信息

F508del-CFTR (Cell-free assay)

溶解度 *

In vitro	DMSO	95 mg/mL (182.51 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.21 mL	96.06 mL	192.12 mL
0.5 mM	3.84 mL	19.21 mL	38.42 mL
1 mM	1.92 mL	9.61 mL	19.21 mL
5 mM	0.38 mL	1.92 mL	3.84 mL

*The above data is based on the productmolecular weight 520.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A12519
M. Wt	520.5
Formula	C26H27F3N2O6
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1152311-62-0
Synonyms	VX661, VX 661
SMILES	CC(C)(CO)C1=CC2=CC(=C(C=C2N1C[C@H](CO)O)F)NC(=O)C3(CC3)C4=CC5=C(C=C4)OC(O5)(F)F