|Aurora A (Cell-free assay)||Aurora C (Cell-free assay)||Aurora B (Cell-free assay)||FLT3 (Cell-free assay)||Bcr-Abl (Cell-free assay)|
|0.6 nM(Ki app)||4.6 nM(Ki app)||18 nM(Ki app)||30 nM(Ki)||30 nM(Ki)|
|In vitro (25°C)||DMSO||93 mg/mL (200.17 mM)|
|Water||<1 mg/mL (<1 mM)|
|Ethanol||<1 mg/mL (<1 mM)|
|In vivo||30% PEG400/0.5% Tween80/5% propylene glycol||30 mg/mL|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||21.52 mL||107.62 mL||215.24 mL|
|0.5 mM||4.3 mL||21.52 mL||43.05 mL|
|1 mM||2.15 mL||10.76 mL||21.52 mL|
|5 mM||0.43 mL||2.15 mL||4.3 mL|
*The above data is based on the productmolecular weight 464.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|MECHANISM OF ACTION||Inhibitor|
|Storage||at -20°C 3 years Powder|
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