VZ185

目录号: A18685

dual BRD7/9 PROTAC degrader

VZ185

VZ185 Chemical Structure

CAS NO. 2306193-61-1

VZ185 is a potent, fast, and selective dual BRD7/9 PROTAC degrader with DC50s of 4.5 and 1.8 nM, respectively.

库存: 现货

规格 价格 数量
5 mg
¥ 3,500.00
10 mg
¥ 6,500.00
50 mg
¥ 20,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

VZ185 is a potent, fast, and selective dual BRD7/9 PROTAC degrader with DC50s of 4.5 and 1.8 nM, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 10.05 mL 50.24 mL 100.48 mL
0.5 mM 2.01 mL 10.05 mL 20.1 mL
1 mM 1 mL 5.02 mL 10.05 mL
5 mM 0.2 mL 1 mL 2.01 mL

*The above data is based on the productmolecular weight 995.21. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A18685
作用机制 Degrader (降解剂)
M. Wt 995.21
Formula C53H67FN8O8S
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 2306193-61-1
Synonyms VZ-185, VZ 185
SMILES O=C([C@H]1N(C([C@@H](NC(C2(F)CC2)=O)C(C)(C)C)=O)C[C@H](O)C1)NCC3=CC=C(C4=C(C)N=CS4)C=C3OCCCCCN5CCN(CC6=C(OC)C=C(C(C7=CC=NC=C87)=CN(C)C8=O)C=C6OC)CC5

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