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WAY-100635最初被认为是选择性的5-HT1A受体拮抗剂，但随后的研究表明它也可作为D4受体的有效全效激动剂。
| In vitro (25°C) | DMSO | 74 mg/mL (137.38 mM) | |
| Water | Insoluble | ||
| Ethanol | 74 mg/mL (137.38 mM) | ||
| In vivo | 2% DMSO+40% PEG 300+2% Tween 80+ddH2O | 9 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.67 mL | 118.33 mL | 236.65 mL |
| 0.5 mM | 4.73 mL | 23.67 mL | 47.33 mL |
| 1 mM | 2.37 mL | 11.83 mL | 23.67 mL |
| 5 mM | 0.47 mL | 2.37 mL | 4.73 mL |
*The above data is based on the productmolecular weight 422.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A11182 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 422.56 |
| Formula | C25H34N4O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 162760-96-5 |
| Synonyms | WAY100635 |
| SMILES | COC1=CC=CC=C1N2CCN(CC2)CCN(C3=CC=CC=N3)C(=O)C4CCCCC4 |
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