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FXR 激动剂

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产品目录号: A11186


产品名 目录号 价格 数量
WAY-362450 5mg A11186-5
¥ 900.00
WAY-362450 10mg A11186-10
¥ 1,500.00
WAY-362450 50mg A11186-50
¥ 4,800.00
WAY-362450 100mg A11186-100
¥ 7,800.00
WAY-362450 10mM * 1mL in DMSO A11186-10mM-D
¥ 1,000.00



WAY-362450 is a highly potent, selective, and orally bioavailable farnesoid X receptor (FXR) agonist (EC50: 4 nM, eff=149%).





顾客使用 Adooq 产品发表的高质量科研文献

Chemical Information

目录号 A11186
Mechanism of action Agonist
分子量 438.47
化学分子式 C25H24F2N2O3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 629664-81-9
Synonyms WAY362450, XL335
SMILES code CC(C)OC(=O)C1=CN(CC(C2=C1NC3=CC=CC=C32)(C)C)C(=O)C4=CC(=C(C=C4)F)F
化学名称 3-(3,4-Difluorobenzoyl)-1,2,3,6-tetrahydro-1,1-dimethylazepino[4,5-b]indole-5-carboxylic acid 1-methylethyl ester



WAY-362450 is a highly potent, selective, and orally bioavailable farnesoid X receptor (FXR) agonist (EC50: 4 nM, eff=149%).

4 nM(EC50)


Solubility (25°C) * In vitro DMSO 33 mg/mL (75.26 mM)
Water <1 mg/mL (<1 mM)
Ethanol 2 mg/mL (4.56 mM)
In vivo NMP/polyethylene glycol 300 (10/90, v/v) 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.81 mL 114.03 mL 228.07mL
0.5 mM 4.56 mL 22.81 mL 45.61 mL
1 mM 2.28 mL 11.4 mL 22.81 mL
5 mM 0.46 mL 2.28 mL 4.56 mL

*The above data is based on the productmolecular weight 438.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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