WAY-362450

目录号: A11186

FXR agonist

WAY-362450

WAY-362450 Chemical Structure

CAS NO. 629664-81-9

WAY-362450 is a highly potent, selective, and orally bioavailable farnesoid X receptor (FXR) agonist (EC50: 4 nM, eff=149%).

库存: 现货

规格 价格 数量
5 mg
¥ 900.00
10 mg
¥ 1,500.00
50 mg
¥ 4,800.00
100 mg
¥ 7,800.00
10mM * 1mL in DMSO
¥ 1,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

WAY-362450 is a highly potent, selective, and orally bioavailable farnesoid X receptor (FXR) agonist (EC50: 4 nM, eff=149%).

Targets
FXR
4 nM(EC50)
In vitro (25°C) DMSO 33 mg/mL (75.26 mM)
Water <1 mg/mL (<1 mM)
Ethanol 2 mg/mL (4.56 mM)
In vivo NMP/polyethylene glycol 300 (10/90, v/v) 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.81 mL 114.03 mL 228.07 mL
0.5 mM 4.56 mL 22.81 mL 45.61 mL
1 mM 2.28 mL 11.4 mL 22.81 mL
5 mM 0.46 mL 2.28 mL 4.56 mL

*The above data is based on the productmolecular weight 438.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11186
MECHANISM OF ACTION Agonist
M. Wt 438.47
Formula C25H24F2N2O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 629664-81-9
Synonyms WAY362450, XL335
SMILES CC(C)OC(=O)C1=CN(CC(C2=C1NC3=CC=CC=C32)(C)C)C(=O)C4=CC(=C(C=C4)F)F

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