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WAY-600

mTOR 抑制剂

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产品目录号: A11188

库存状态:中国现货中国现货

产品名 目录号 价格 数量
WAY-600 5mg A11188-5
¥ 1,500.00
WAY-600 10mg A11188-10
¥ 2,500.00
WAY-600 50mg A11188-50
¥ 5,500.00
WAY-600 100mg A11188-100
¥ 9,000.00
WAY-600 10mM * 1mL in DMSO A11188-10mM-D
¥ 2,070.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

WAY-600 is a single digit nanomolar inhibitor of the mTOR kinases, with significant selectivity for these enzymes over phosphatidylinositol 3-kinase (PI3K) isofoms (>100-fold).

WAY-600

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Chemical Information

目录号 A11188
Mechanism of action Inhibitor
分子量 494.59
化学分子式 C28H30N8O
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1062159-35-6
Synonyms WAY600
SMILES code C1CN(CCC1N2C3=C(C=N2)C(=NC(=N3)C4=CC5=C(C=C4)NC=C5)N6CCOCC6)CC7=CN=CC=C7
化学名称 6-(1H-Indol-5-yl)-4-(4-morpholinyl)-1-[1-(3-pyridinylmethyl)-4-piperidinyl]-1H-pyrazolo[3,4-d]pyrimidine

生物活性

Description

WAY-600 is a single digit nanomolar inhibitor of the mTOR kinases, with significant selectivity for these enzymes over phosphatidylinositol 3-kinase (PI3K) isofoms (>100-fold).

溶解性

Solubility (25°C)* In vitro DMSO 22 mg/mL (44.48 mM)
Water <1 mg/mL (<1 mM)
Ethanol 2 mg/mL (4.04 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.22 mL 101.09 mL 202.19mL
0.5 mM 4.04 mL 20.22 mL 40.44 mL
1 mM 2.02 mL 10.11 mL 20.22 mL
5 mM 0.4 mL 2.02 mL 4.04 mL

*The above data is based on the productmolecular weight 494.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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