WAY-600

目录号: A11188

mTOR 抑制剂

WAY-600

WAY-600 Chemical Structure

CAS NO. 1062159-35-6

WAY-600是一种有效的,ATP竞争性的,选择性的mTOR抑制剂,IC50为9 nM;抑制mTORC1/P-S6K(T389)和mTORC2/P-AKT(S473),但不抑制P-AKT(T308);作用于mTOR比作用于PI3Kα(>100倍)和PI3Kγ(>500倍)选择性高。

库存: 现货

规格 价格 数量
5 mg
¥ 1,500.00
10 mg
¥ 2,500.00
50 mg
¥ 5,500.00
100 mg
¥ 9,000.00
10mM * 1mL in DMSO
¥ 2,070.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

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WAY-600是一种有效的,ATP竞争性的,选择性的mTOR抑制剂,IC50为9 nM;抑制mTORC1/P-S6K(T389)和mTORC2/P-AKT(S473),但不抑制P-AKT(T308);作用于mTOR比作用于PI3Kα(>100倍)和PI3Kγ(>500倍)选择性高。
In vitro DMSO 22 mg/mL (44.48 mM)
Water <1 mg/mL (<1 mM)
Ethanol 2 mg/mL (4.04 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.22 mL 101.09 mL 202.19 mL
0.5 mM 4.04 mL 20.22 mL 40.44 mL
1 mM 2.02 mL 10.11 mL 20.22 mL
5 mM 0.4 mL 2.02 mL 4.04 mL

*The above data is based on the productmolecular weight 494.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11188
作用机制 Inhibitor (抑制剂)
M. Wt 494.59
Formula C28H30N8O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1062159-35-6
Synonyms WAY600
SMILES C1CN(CCC1N2C3=C(C=N2)C(=NC(=N3)C4=CC5=C(C=C4)NC=C5)N6CCOCC6)CC7=CN=CC=C7

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