产品详情
WEHI-9625 is a tricyclic sulfone small molecule inhibitor of apoptosis with an EC50 of 69 nM. WEHI-9625 binds to VDAC2 and promotes its ability to inhibit apoptosis driven by mouse BAK, but is completely inactive against both human BAK and the closely related apoptosis effector BAX.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 16.84 mL | 84.22 mL | 168.43 mL |
0.5 mM | 3.37 mL | 16.84 mL | 33.69 mL |
1 mM | 1.68 mL | 8.42 mL | 16.84 mL |
5 mM | 0.34 mL | 1.68 mL | 3.37 mL |
*The above data is based on the productmolecular weight 593.71. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A18351 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 593.71 |
Formula | C34H27NO5S2 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | N/A |
Synonyms | WEHI9625, WEHI 9625 |
SMILES | O=C(C(S1)=CC(CS2(=O)=O)=C1C3=C2C=C(C4=CC=CC=C4C(C5=CC=C(OC)C=C5)=O)C=C3)NCC6=CC=C(C)C=C6 |
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