WH 4-023

Name: WH 4-023
SKU: A14117

目录号: A14117

dual Lck/Src 抑制剂

WH 4-023 Chemical Structure

CAS NO. 837422-57-8

WH-4-023是一种有效的选择性Lck/Src双重抑制剂，对Lck和Src激酶的IC50分别为2 nM/6 nM。

库存：现货

规格	价格	数量
10 mg	￥ 1,200.00
25 mg	￥ 2,500.00
50 mg	￥ 4,000.00
10mM * 1mL in DMSO	￥ 1,000.00

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生物活性

WH-4-023是一种有效的选择性Lck/Src双重抑制剂，对Lck和Src激酶的IC50分别为2 nM/6 nM。

靶点信息

Lck (Cell-free assay)	Src (Cell-free assay)
2 nM	6 nM

溶解度 *

In vitro (25°C)	DMSO	Warmed: 12 mg/mL (21.1 mM)
	Water	Insoluble
	Ethanol	Warmed: 6 mg/mL (10.55 mM)
In vivo	5% DMSO+30% PEG 300+5% Tween 80+ddH2O	1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.58 mL	87.92 mL	175.85 mL
0.5 mM	3.52 mL	17.58 mL	35.17 mL
1 mM	1.76 mL	8.79 mL	17.58 mL
5 mM	0.35 mL	1.76 mL	3.52 mL

*The above data is based on the productmolecular weight 568.67. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A14117
作用机制	Inhibitor (抑制剂)
M. Wt	568.67
Formula	C32H36N6O4
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	837422-57-8
Synonyms	WH-4-023,WH4-023
SMILES	CC1=C(C(=CC=C1)C)OC(=O)N(C2=C(C=C(C=C2)OC)OC)C3=NC(=NC=C3)NC4=CC=C(C=C4)N5CCN(CC5)C