WH 4-023
目录号: A14117
dual Lck/Src 抑制剂
WH-4-023 是一种高效且选择性的双重 Lck/Src 抑制剂,其对 Lck 和 Src 激酶的 IC50 分别为 2 nM 和 6 nM。
| Discription | WH-4-023 is a potent and selective dual Lck/Src inhibitor with IC50 of 2 nM/6 nM for Lck and Src kinase respectively. | ||
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| Targets |
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| 目录号 | A14117 |
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| 分子式 | C32H36N6O4 |
| 分子量 | 568.67 |
| CAS号 | 837422-57-8 |
| SMILES | CC1=C(C(=CC=C1)C)OC(=O)N(C2=C(C=C(C=C2)OC)OC)C3=NC(=NC=C3)NC4=CC=C(C=C4)N5CCN(CC5)C |
| 其他名称 | WH-4-023,WH4-023 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | Warmed: 12 mg/mL (21.1 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 6 mg/mL (10.55 mM) | ||
| In vivo | 5% DMSO+30% PEG 300+5% Tween 80+ddH2O | 1 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.58 mL | 87.92 mL | 175.85 mL |
| 0.5 mM | 3.52 mL | 17.58 mL | 35.17 mL |
| 1 mM | 1.76 mL | 8.79 mL | 17.58 mL |
| 5 mM | 0.35 mL | 1.76 mL | 3.52 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2