WHI-P 154

目录号: A14049

JAK3 抑制剂

WHI-P 154 Chemical Structure

CAS NO. 211555-04-3

WHI-P 154 is a JAK3 inhibitor with IC50 = 1.8uM. WHI-P 154 also Inhibits STAT1 activation, iNOS expression and NO production in macrophages in vitro.

库存: 现货

规格 价格 数量
10 mg
¥ 800.00
25 mg
¥ 1,600.00
50 mg
¥ 3,000.00
10mM * 1mL in DMSO
¥ 850.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

WHI-P 154 is a JAK3 inhibitor with IC50 = 1.8uM. WHI-P 154 also Inhibits STAT1 activation, iNOS expression and NO production in macrophages in vitro.
靶点信息
EGFR VEGFR Src JAK3
4 nM100 nM100 nM1.8 μM
In vitro (25°C) DMSO 75 mg/mL (199.36 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.58 mL 132.91 mL 265.82 mL
0.5 mM 5.32 mL 26.58 mL 53.16 mL
1 mM 2.66 mL 13.29 mL 26.58 mL
5 mM 0.53 mL 2.66 mL 5.32 mL

*The above data is based on the productmolecular weight 376.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A14049
MECHANISM OF ACTION Inhibitor
M. Wt 376.2
Formula C16H14BrN3O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 211555-04-3
Synonyms WHI-P154
SMILES COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)O)Br)OC

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