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WHI-P 154

JAK3 抑制剂

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产品目录号: A14049


产品名 目录号 价格 数量
WHI-P 154 10mg A14049-10
¥ 800.00
WHI-P 154 25mg A14049-25
¥ 1,600.00
WHI-P 154 50mg A14049-50
¥ 3,000.00
WHI-P 154 10mM * 1mL in DMSO A14049-10mM-D
¥ 850.00



WHI-P 154 is a JAK3 inhibitor with IC50 = 1.8uM. WHI-P 154 also Inhibits STAT1 activation, iNOS expression and NO production in macrophages in vitro.

WHI-P 154




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Chemical Information

目录号 A14049
Mechanism of action Inhibitor
分子量 376.2
化学分子式 C16H14BrN3O3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 211555-04-3
Synonyms WHI-P154
SMILES code COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)O)Br)OC
化学名称 2-Bromo-4-[(6,7-dimethoxy-4-quinazolinyl)amino]phenol


WHI-P 154 is a JAK3 inhibitor with IC50 = 1.8uM. WHI-P 154 also Inhibits STAT1 activation, iNOS expression and NO production in macrophages in vitro.
4 nM100 nM100 nM1.8 μM


Solubility (25°C) * In vitro DMSO 75 mg/mL (199.36 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.58 mL 132.91 mL 265.82mL
0.5 mM 5.32 mL 26.58 mL 53.16 mL
1 mM 2.66 mL 13.29 mL 26.58 mL
5 mM 0.53 mL 2.66 mL 5.32 mL

*The above data is based on the productmolecular weight 376.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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